Holmium-166 radioembolization for the treatment of patients with liver metastases: design of the phase I HEPAR trial

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Holmium-166 radioembolization for the treatment of patients with liver metastases: design of the phase I HEPAR trial

BACKGROUND Intra-arterial radioembolization with yttrium-90 microspheres ( 90Y-RE) is an increasingly used therapy for patients with unresectable liver malignancies. Over the last decade, radioactive holmium-166 poly(L-lactic acid) microspheres ( 166Ho-PLLA-MS) have been developed as a possible alternative to 90Y-RE. Next to high-energy beta-radiation, 166Ho also emits gamma-radiation, which al...

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Radioembolization treatment for liver metastases

The liver is an organ that, due to vascularisation and functions, is prone to metastases. Most liver metastases are observed in cases of gastrointestinal cancers in: stomach, colon, gallbladder, and bile ducts. Metastatic lesions are also observed in lung, breast, thyroid, kidney, and pancreatic cancer. One of the best known and most effective ways of liver lesion treatment is Metastasectomy. U...

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ژورنال

عنوان ژورنال: Journal of Experimental & Clinical Cancer Research

سال: 2010

ISSN: 1756-9966

DOI: 10.1186/1756-9966-29-70